WebDec 20, 2024 · Altered hepatic drug metabolism due to underlying liver disease can result in higher or more persistent drug levels, thereby causing increased systemic toxicity …
Modified cisplatin/interferon α‐2b/doxorubicin/5‐fluorouracil …
WebApr 20, 2024 · Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the most lethal disease in the population with cirrhosis [ 1 ]. Based on the World Health Organization estimation, about 660,000 deaths are caused by HCC worldwide per year and half of the mortality occurs in China [ 2 ]. WebApr 5, 2024 · Cisplatin for injectioncan cause dose-related nephrotoxicity, including acute renal failure that becomes more prolonged and severe with repeated courses of the drug. … jesus thank you lyrics and chords
Liver Injury Caused by Drugs - Merck Manuals Consumer Version
WebLiver fibrosis and in particular cirrhosis are the major causes of morbidity and mortality of patients with chronic liver disease. Their prevention or reversal have become major endpoints in clinical trials with novel liver specific drugs. WebFeb 17, 2024 · The Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis trial used a half dose of pegylated interferon versus no treatment; the treatment was to be administered for 3.5 years. The aim was to reduce progression of chronic hepatitis C, particularly in the development of HCC. WebSep 15, 2024 · Cisplatin is the prototype platinum coordination complex classified as an alkylating agent and used intravenously in the treatment of several forms of cancer. Cisplatin has been associated with a low rate of serum enzyme elevations and with rare … inspired cctv