WebApr 13, 2024 · DNA binding motif and protein-protein interaction enrichment analysis identified the hepatic nuclear factor, Hnf1a (MODY3 gene in humans), as a strong candidate. The pleiotropic effects of meQTL.5a could contribute to variation in body size and metabolic traits, and influence CpG methylation and epigenetic aging that could have an … WebGPX4 glutathione peroxidase 4, SLC3A2 solute carrier family 3, member 2, SLC7A11 solute carrier family 7 (L-type amino acid transporter), ... DNA methylation, and histone modification . LSH, as an oncogene, has been found to be highly expressed in lung cancer tissues, and is positively correlated with the expression of GINS4.
GPX4 - Wikipedia
WebApr 2, 2024 · Collectively, CREB, GPX4, EP300 and 4-HNE, which are related to lipid peroxidation, were closely related to tumor size and stage, and the tumors with a high … WebGlutathione peroxidase 4 (GPX4) is one of the most important antioxidant enzymes. As the key regulator of ferroptosis, GPX4 has attracted considerable attention in the fields of cancer, cardiovascular, and neuroscience research in the past 10 years. How to regulate GPX4 activity has become a hot topic nowadays. GPX4 protein level is regulated … siesta key vacations packages
WTAP-mediated GPX4 m6A methylation triggers PASMCs
WebDec 14, 2024 · Methylation of the Nrf2 promoter was analyzed by bisulfite sequencing and pyrosequencing. Results Ferroptosis was involved in COPD and glutathione peroxidase 4 (GPX4) expression was downregulated in the COPD group. ... Keywords: copd,nrf2,ferroptosis,gpx4,dna methylation,oxidative stress,inflammation. Data … WebFeb 8, 2024 · By Southern analysis of genomic DNA from human/hamster somatic cell hybrids, Chu (1994) showed that the GPX4 gene is located on chromosome 19. By fluorescence in situ hybridization, Kelner and Montoya (1998) assigned the gene to chromosome 19p13.3. WebMar 21, 2024 · GPX4 (Glutathione Peroxidase 4) is a Protein Coding gene. Diseases associated with GPX4 include Spondylometaphyseal Dysplasia, Sedaghatian Type and … the power of teamwork book