Granulophysin

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August undefined, 2024

WebNormal human peripheral blood cells were stained with CD193 (CCR3) Monoclonal Antibody, PE (Product # 12-1939-42) and IgE Monoclonal Antibody, FITC (Product # 11-6986-42) only (blue histogram), or stained with CD63 Monoclonal Antibody, NovaFluor Red 700 (Product # H074T03R03) (purple histogram). WebThe H5C6 monoclonal antibody specifically binds to CD63. CD63 is a 53 kDa, type III lysosomal glycoprotein, expressed on activated platelets, monocytes and macrophages. This molecule is also referred to in the literature as LIMP, gp55, melanoma-associated antigen ME491, Pltgp40, LAMP-3 and is a member of the tetraspan transmembrane 4 …

CD63 Antibodies - Beckman Coulter Life Sciences

WebApr 1, 1994 · In lysates prepared from prostasomes, a broad band of 32 to 37 kd was detected by Western blotting. Conclusion This report defines granulophysin as a constituent membrane molecule of prostasomes that may serve as a useful marker in elucidation of prostasome function. Key Words Human seminal plasma prostasomes … WebSep 1, 1992 · An antigen-capture sandwich enzyme-linked immunosorbent assay (ELISA) was developed for a novel protein granulophysin, a constituent of the platelet dense … chip shop otley

granulophysin - Wiktionary

WebNational Center for Biotechnology Information Webmolecule, CD63_HUMAN, gp55, Granulophysin, LAMP 3, LAMP-3, LAMP3, LIMP, Lysosomal-associated membrane protein 3, Lysosome associated membrane glycoprotein 3, Mast cell antigen AD1, ME491, Melanoma 1 antigen, Melanoma associated antigen ME491, Melanoma associated antigen MLA1, Melanoma-associated antigen ME491, … WebCD63 molecule. Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and ... graph conflictbehavior

Megakaryocyte dense granule components are sorted in …

WebDescription: Homo sapiens CD63 molecule (CD63), transcript variant 3, mRNA. (from RefSeq NM_001257389) RefSeq Summary (NM_001257389): The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the … Webprotein called granulophysin ( 15, 16), which is decreased in the Hermansky-Pudlak syndrome (15, 17). Ourresults thus providethefirstidentification … graph connector apiWebApr 1, 1993 · The levels and expression of the proteins CD63 and granulophysin in platelets from control and from a Hermansky-Pudlak syndrome subject (a condition … chip shop oswestry

"WebAbout This Kit. Human CD63 quantitates human CD63 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD63. CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. " - Granulophysin

Granulophysin

Web2024 CiteAb Awards - View the winners now! ... Search WebSep 1, 1992 · Granulophysin levels were only low in forms of delta-SPD associated with albinism. Granulophysin levels in platelet homogenates of 30 patients with the Hermansky-Pudlak syndrome form of delta-SPD were 1/4 to 1/5 of levels in controls or obligate heterozygotes. Two patients with the Chediak-Higashi form of delta-SPD syndrome also …

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WebUniProt Accession Number of Target Protein: P08962 Alternative Name(s) of Target: Granulophysin; LAMP-3; ME491; MLA1; OMA81H; TSPAN30; LAMP3 Immunogen: Human monocytes. Specificity: This antibody binds to CD63 on monocytes and activated neutrophils. Application Notes: This antibody binds to CD63, a membrane-spanning … WebPE-Cy7 is a tandem fluorochrome composed of R-phycoerythrin (PE), which is excited by 488-nm light and serves as an energy donor, coupled to the cyanine dye Cy7, which acts as an energy acceptor and fluoresces maximally at 780 nm. PE-Cy7 tandem fluorochrome emission is collected in a detector for fluorescence wavelengths of 750 nm and higher.

WebThe H5C6 monoclonal antibody specifically binds to CD63. CD63 is a 53 kDa, type III lysosomal glycoprotein, expressed on activated platelets, monocytes and macrophages. This molecule is also referred to in the literature as LIMP, gp55, melanoma-associated antigen ME491, Pltgp40, LAMP-3 and is a member of the tetraspan transmembrane 4 … WebNaked mole-rats are long-lived animals that show unusual resistance to hypoxia, cancer and ageing. Protein deimination is an irreversible post-translational modification caused by the peptidylarginine deiminase (PAD) family of enzymes, which convert arginine into citrulline in target proteins. Protein deimination can cause structural and functional protein changes, …

WebJun 1, 1994 · Abstract. Granulophysin, a protein described in platelet dense granule membranes, has been shown to be similar or identical to CD63, a lysosomal … WebNov 6, 2024 · Level of granulophysin on the platelet surface. A, 5‐ HT /catecholamine‐treated or ‐untreated platelets were evaluated by measuring the level of granulophysin, a surrogate marker for dense‐granule …

WebJun 1, 1994 · Granulophysin expression on the surface membrane of the neutrophil is increased following stimulation of the cells, demonstrated by flow cytometry and fine structural immunocytochemistry. A similar pattern is shown for an anti-CD63 antibody. Incubation of activated neutrophils with D545, a monoclonal antibody to granulophysin, …

WebApr 1, 1993 · The levels and expression of the proteins CD63 and granulophysin in platelets from control and from a Hermansky-Pudlak syndrome subject (a condition characterized by dense granule and lysosomal deficiencies and the accumulation of ceroid-like material in reticuloendothelial cells) were examined. Immunofluorescence studies … graph connector capacityWebnoun. gran· u· lo· poi· e· sis - (ˌ)lō-ˌpȯi-ˈē-səs. plural granulopoieses -ˌsēz. : the formation of blood granulocytes typically in the bone marrow. called also granulocytopoiesis. … chip shop owner driven outWebJun 15, 2000 · Arrowheads indicate granulophysin (10-nm gold particles), and arrows indicate α-granule marker von Willebrand factor (5-nm gold particles). Both proteins can be found within the same MVB, but they are segregated from each other in distinct microvesicles. Granulophysin is also preferentially associated with the limiting … graph connector for searchWebJun 15, 2000 · It can only be identified by GPIb-specific expression on its plasma membrane (pm). Granulophysin labels the membrane of vacuolar structures, which can be … graph connector licensingWebAnti-MLA1 antibody, anti-TSPAN30 antibody, anti-CD63 antigen antibody, anti-Granulophysin antibody, anti-Lysosomal-associated membrane protein 3 antibody, anti-LAMP-3 antibody, anti-Melanoma-associated antigen ME491 antibody, anti-OMA81H antibody, anti-O: Produktbeschreibung. Mouse monoclonal antibody to CD63: graph concaving up chip shop owner celebrating queens deathWebJul 1, 1992 · We recently reported the characterization of a platelet granule membrane protein of molecular weight (mol wt) 40,000 called granulophysin (Gerrard et al: Blood … graph confusion matrix python