Lithoplocamia lithistoides

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August undefined, 2024

Web10 jul. 2013 · Paclitaxel is arguably the most well-known and commercially successful mitosis inhibitor; intriguingly, these new compounds isolated from the Madagascan sponge Lithoplocamia lithistoides show a distinct biochemical mechanism of … WebDendy, A. (1922). Report on the Sigmatotetraxonida collected by H.M.S.'Sealark' in the Indian Ocean. In: Reports of the Percy Sladen Trust Expedition to the ...

Frontiers Antitumoral Effect of Plocabulin in High Grade Serous ...

WebLithoplocamia lithistoides en Lithoplocamia · Bekijk meer » Unionpedia is een concept map of een semantisch netwerk organiseerde als een encyclopedie of een … WebOriginally isolated from the Madagascan marine sponge Lithoplocamia lithistoides, plocabulin is now obtained by total synthesis [3]. Plocabulin binds tubulin with high a nity, reducing its polymerization and depolymerization to a similar extent and thereby inhibiting microtubule dynamicity (Figure1) [4–6]. chut awell

Lithoplocamia lithistoides - Wikiwand

• Lithoplocamia atlantica (Lévi & Vacelet, 1958) • Lithoplocamia dolichosclera Lévi & Lévi, 1983 • Lithoplocamia indica Pulitzer-Finali, 1993 • Lithoplocamia lithistoides Dendy, 1922 WebPM050489 is an effective polyketone inhibitor of Microtubule/Tubulin that can be isolated from Madagascan sponge Lithoplocamia lithistoides. PM050489 inhibits mitosis with an IC50 value of 26.4 nM. PM050489 has antitumor activity and can be used in cancer research [1] [2] . PM050489 inhibits the activity of HT-29, A-549 and MDA-MB-231 cells ... WebGlobal Biodiversity Information Facility. Free and Open Access to Biodiversity Data. dfrobot audio analyzer

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WebLithoplocamia lithistoides Dendy, 1922 AphiaID 167995 (urn:lsid:marinespecies.org:taxname:167995) Classification Biota Animalia (Kingdom) … WebGenus: Lithoplocamia Species (6): L. atlantica – L. dolichosclera – L. indica – L. lithistoides – L. minor – L. tuberculata. Name . Lithoplocamia Dendy, 1922 References … dfrobot ads1115Web1 nov. 2024 · Plocabulin, a marine natural polyketide isolated from the sponge Lithoplocamia lithistoides, is a novel and potent microtubule-destabilizing agent. … dfrobot address

"WebLithoplocamia lithistoides is 'n sponsspesie in die taksonomiese indeling van die Demospongiae (gewone sponse). Die liggaam van die spons bestaan uit kieselnaalde … " - Lithoplocamia lithistoides

Lithoplocamia lithistoides

First-in-human phase I study of the microtubule inhibitor …

Web1 apr. 2014 · Abstract. PM060184 belongs to a new family of tubulin-binding agents originally isolated from the marine sponge Lithoplocamia lithistoides. This compound … WebLithoplocamia lithistoides (Q2418850) From Wikidata. Jump to navigation Jump to search. species of sponge. edit. Language Label Description Also known as; English: …

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WebLithoplocamia lithistoides is een spons soort in de taxonomische indeling van de gewone sponzen (Demospongiae). Het lichaam van de spons bestaat uit kiezelnaalden en sponginevezels, en is in staat om veel water op te nemen. De spons behoort tot het … Web17 mrt. 2024 · Plocabulin (PM060184/PM184, PharmaMar) is a compound of marine origin derived from the Madagascan sponge Lithoplocamia lithistoides. Plocabulin belongs to a family of tubulin-binding agents that inhibits tubulin polymerization by binding to the dimer’s end, with one of the highest known affinities among tubulin-binding agents.

Web21 jan. 2024 · Kahalalide F has displayed potent cytotoxicity against cancer cells of the breast (BT-474, MCF7, MDA-231, and SK-BR-3), colon (HT29 and LoVo), liver (Hep G2), lung adenocarcinoma (A549), ovaries,... WebLithoplocamia lithistoides adalah spesies spons yang tergolong dalam kelas Demospongiae. Spesies ini juga merupakan bagian dari genus Lithoplocamia dan famili …

WebLithoplocamia lithistoides. Lithoplocamia lithistoides adalah spesies spons yang tergolong dalam kelas Demospongiae. Spesies ini juga merupakan bagian dari genus Lithoplocamia dan famili Raspailiidae. Nama ilmiah spesies ini pertama kali diterbitkan pada tahun 1922 oleh Dendy. Seperti spons pada umumnya, spesies ini memiliki tubuh … WebPHASE I STUDIES First-in-human phase I study of the microtubule inhibitor plocabulin in patients with advanced solid tumors Elena Elez1 & Carlos Gomez-Roca2 & Arturo Soto Matos-Pita3 & Guillem Argiles1 & Thibaud Valentin2 & Cinthya Coronado3 & Jorge Iglesias3 & Teresa Macarulla1 & Sarah Betrian2 & Salvador Fudio3 & Katrin Zaragoza3 & Josep …

WebLithoplocamia is een geslacht van sponsdieren uit de klasse van de Demospongiae . For faster navigation, this Iframe is preloading the Wikiwand page for Lithoplocamia . Home

Web11 jun. 2024 · Lithoplocamia lithistoides Dendy, 1922. Accessed through: Odido, M.; Appeltans, W.; BelHassen, M.; Mussai, P.; Nsiangango, S.E.; Vandepitte, L.; Wambiji, … dfrobot 7 inch display hdmi datasheetWeb29 feb. 2016 · PM184 is a marine -derive drug found in a sponge called Lithoplocamia lithistoides. This drug candidate is a microtubule inhibitor that targets a protein called tubulin in a novel way. It blocks cancer growth by impairing cell division of tumour cells through the inhibition of a crucial process called mitosis. chut athosWeb1 nov. 2024 · Plocabulin, a marine natural polyketide isolated from the sponge Lithoplocamia lithistoides, is a novel and potent microtubule-destabilizing agent. … chutball dfrobot 5.8ghz microwave radar moduleWebThese compounds were active against one or more drug-resistant pathogens such as methicillin-resistant Staphylococcus aureus, methicillin-resistant Staphylococcus epidermidis, vancomycin-resistant Enterococci, multidrug-resistant Mycobacterium tuberculosis, and amphotericin B-resistant Candida albicans. dfrobot analog sound sensorWebLithoplocamia is een geslacht van sponsdieren uit de klasse van de Demospongiae (gewone sponzen). 7 relaties: Lithoplocamia atlantica , Lithoplocamia dolichosclera , … dfrobot audio analyzer v2Web7 dec. 2024 · Plocabulin (PM184; Fig. 8) and its chloro-derivative (Fig. 8; PM-050489) were isolated by PharmaMar scientists from the sponge Lithoplocamia lithistoides, but due to the low levels in the extract, both … dfrobot as7341