WebFinally, ST6GalNac-I is an enzyme associated with the sialylation of Tn antigen localized on the external glycosylated region of MUC1-VNTR. 13 Moreover, sialyl-Tn is known to play a … WebSialyl-Tn is a carbohydrate antigen overexpressed in several epithelial cancers including breast cancer, and usually associated with poor prognosis. Sialyl-Tn is synthesized by a …
Sialyl Tn抗体[STn 219] Abcam中文官网
WebJul 16, 2013 · In many different human disorders, the cellular glycome is altered. An interesting but poorly understood alteration occurs in the mucin-type O-glycome, in which … WebJun 29, 2024 · Sialyl-Tn antigen [STn, NeuAcα(2,6)GalNAcα-O-Ser/Thr] is abundantly expressed on many epithelium-derived tumors (e.g., breast, pancreas, prostate, lung, … the panics don\u0027t fight it
Carlo Pifferi - Postdoctoral Researcher - Center for Molecular ...
WebThe compositions and methods are described for generating an immune response to a tumor associated antigen such as MUC1. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a neoplasm expressing the tumor associated … WebSep 14, 2024 · In some embodiments, the composition comprises NeuAcα2-3Galβ1-3GalNAc (Sialyl-T antigen), NeuAcα2-6GalNAc (Sialyl Tn antigen), and NeuAcα2-3Galβ1-3(NeuAcα2- 6)GalNAc (Disialyl T antigen). [0026] In some embodiments, the composition has substantially no free glycans. In some embodiments, the composition has a pH of … WebJu, T., Wang, Y., Aryal, R. P., Lehoux, S. D., Ding, X., Kudelka, M. R., … Cummings, R. D. (2013). Tn and sialyl-Tn antigens, aberrantO-glycomics as human disease ... shut this thing down